Polynucleotides at Laser Skin Clinics in Wolverhampton, priced at £150.00. Bio-regenerative polynucleotide therapy that works at a cellular level to hydrate, repair, and rejuvenate skin — stimulating fibroblast activity and restoring your skin's natural regenerative capac.... To book, contact us on WhatsApp at 07798 983387 or call 01902 256 667.
Bio-Regenerative Therapy
Polynucleotides

What are Polynucleotides?
Polynucleotides are a next-generation regenerative injectable that works by stimulating the skin's own repair and renewal mechanisms at a cellular level. Derived from purified salmon/trout DNA, polynucleotide injections promote tissue regeneration, improve hydration, reduce inflammation, and stimulate the production of new collagen and elastin — addressing skin quality concerns that traditional treatments cannot reach.
- Stimulates cellular regeneration and tissue repair from within the skin.
- Improves skin hydration, elasticity, and overall quality over a course of treatments
- Particularly effective for under-eye hollowing, fine lines, and dullness
- Natural and biocompatible — derived from purified salmon PDRN
Polynucleotides represent a significant advance in regenerative aesthetics — offering lasting improvements in skin quality that go beyond what hydrating or volumising treatments alone can achieve.
What It Treats
Under-Eye Dark Circles & Hollowing
Regenerates delicate periorbital tissue to reduce shadows and crepiness
Fine Lines & Crepey Skin
Stimulates collagen and elastin for smoother, firmer skin texture
Skin Laxity & Loss of Firmness
Bio-regenerative action restores structural support from within
Dehydrated Ageing Skin
Deep hydration through tissue regeneration, not just surface moisture
Dull, Tired Complexion
Revitalises skin radiance by stimulating cellular renewal
Neck & Décolletage
Treats crepey, sun-damaged skin on the neck and chest
Polynucleotides vs Dermal Fillers
Dermal Fillers
- Add volume by physically filling the area with hyaluronic acid gel
- Immediate visible results
- Results are temporary; gel is gradually absorbed
- Does not improve skin quality itself
- Risk of migration or lumpiness if poorly placed
Polynucleotides at Laser Skin Clinics
- Regenerate your skin from within by stimulating your own collagen and elastin
- Results build gradually over 2–6 weeks as regeneration occurs
- Long-lasting improvement in actual skin quality, not just volume
- Improves hydration, texture, elasticity, and radiance simultaneously
- No risk of migration, works with your body's natural repair processes
How It Works
Consultation
Maxine will assess your skin quality, areas of concern, and medical history. She discusses realistic outcomes and designs a personalised treatment course tailored to your skin's needs.
Treatment Preparation
A topical anaesthetic may be applied for comfort. The treatment area is cleaned and prepared to ensure a sterile, safe procedure.
PDRN Injections
Polynucleotide solution is injected superficially into the target areas using fine needles. Most sessions take 20–30 minutes. A course of 3–4 treatments is typically recommended.
Progressive Regeneration
Results build progressively as the PDRN stimulates collagen synthesis and tissue regeneration. Full results are typically visible 4–8 weeks after completing your course.
Suitability Guide
✓ Ideal For
- ✓ Clients seeking natural skin regeneration without fillers or synthetic products
- ✓ Those wanting to improve skin quality from within rather than add volume
- ✓ Anyone looking specifically for under-eye or delicate-area rejuvenation
- ✓ Clients wanting gradual, natural-looking results that build over a course
- ✓ Those who prefer a bio-regenerative approach to skin ageing
✕ May Not Be Suitable If
- ✕ Allergy to salmon-derived products (PDRN is salmon DNA)
- ✕ Active skin infection or inflammation at injection sites
- ✕ Pregnant or breastfeeding
- ✕ Autoimmune conditions affecting connective tissue
Your Results Timeline
Initial Healing
Mild redness or small bumps may appear at injection sites — this is normal. The PDRN molecules begin activating fibroblast cells to stimulate collagen production.
Hydration Boost
Skin visibly plumps and dewiness improves as the polynucleotides attract and bind moisture in the dermis. Dark circles and hollowness under the eyes begin to reduce.
Skin Quality Improvement
Fine lines soften, skin tone evens, and a healthy glow becomes apparent. Collagen density continues to build from the inside out.
Progressive Refinement
The full regenerative effect is visible — firmer, more resilient skin with improved texture. Results are cumulative; maintenance every 4–6 months is recommended.
Aftercare Guidance
Avoid Touching the Area
Do not massage, press, or apply pressure to treated areas. Small papules at injection sites will resolve. Avoid alcohol and strenuous exercise.
Gentle Skincare Only
Use a gentle cleanser and fragrance-free moisturiser. Avoid retinoids, AHAs, and active serums. Mineral SPF 50+ is essential, especially for eye and face treatments.
Reintroduce Actives Gradually
Resume your regular skincare routine. Results improve progressively — collagen stimulation continues for several months. Book your next session at 4–6 week intervals.
WHY CHOOSE US
Why Laser Skin Clinics
Consultation-Led
Every treatment begins with a thorough assessment of your skin, your concerns, and your goals before we recommend anything.
Medical-Grade Technology
We invest in the same calibre of equipment found in leading UK clinics, not salon-grade alternatives.
Personalised Plans
Your treatment plan is built around you: your skin type, your lifestyle, and your desired outcome.
Established 10+ Years
Trusted by thousands of clients across Wolverhampton and the West Midlands since 2013.
Treatment Pricing
Under Eyes
Full Face
What Our Clients Say
"Had my first polynucleotide session today. The lady who did my session (sorry I didn't ask for her name) was so lovely and made me feel at ease and did my treatment with care. I can't wait to return. Highly recommend."
"Absolutely love going to Laser skin clinic!!! I go for tattoo removal, laser hair removal and polynucleotide injections around eye bags, its worth the pain to see the lovely Maxine and Angel every 6 weeks 🤣. Thank you"
"I can't speak highly enough of Angel and Maxine, the empathy, care, knowledge and kindness they have shown me. Given so much advice and it's not about the money. Such genuine ladies who want to help. I really can't recommend them enough. X"
COMMON QUESTIONS
Frequently Asked Questions
Polynucleotides are purified DNA fragments that stimulate cellular repair and collagen production.
Rather than adding volume like filler, they:
• Improve skin quality
• Support regeneration
• Increase hydration
• Strengthen the dermal structure
They work by activating your skin’s natural repair response.
We use Plinest, a high-quality, medical-grade polynucleotide treatment known for its purity, safety, and clinically proven results. Plinest is widely used in advanced aesthetic medicine to support skin regeneration, improve texture, and enhance overall skin quality.
No.
Dermal fillers add volume immediately.
Polynucleotides improve skin quality gradually by stimulating regeneration and collagen remodelling.
The result is more natural and progressive.
Common areas include:
• Under-eyes
• Face
• Neck
• Décolletage
They are particularly popular for delicate under-eye rejuvenation.
Yes when performed correctly.
Polynucleotides are often chosen specifically for under-eye treatment because they improve skin quality without adding heavy volume.
A consultation ensures correct placement and suitability.
Most clients require 2–3 sessions spaced 2–4 weeks apart.
Maintenance may be recommended every 6–9 months depending on skin goals.
Some improvement in hydration and glow can appear within weeks.
Collagen stimulation continues progressively over 8–12 weeks.
Results improve gradually rather than instantly.
You may experience:
• Mild swelling
• Small injection bumps
• Light bruising
These typically settle within 24–72 hours.
Most clients return to normal activities quickly.
Yes.
Polynucleotides are often combined with:
• Anti-wrinkle treatments
• Skin boosters
• CO₂ resurfacing
• Microneedling
Your consultation determines safe sequencing.
This treatment may not be suitable if:
• Pregnant or breastfeeding
• Active infection in treatment area
• Certain autoimmune conditions
A consultation ensures safety.
We offer flexible payment options to make your treatment as convenient as possible. You can choose to pay per single session or pay in full for a course of treatments for better overall value. We accept card, cash, and bank transfer in clinic.
For added flexibility, we also offer 0% finance through Klarna, allowing you to spread the cost into manageable instalments with a range of payment options available, subject to eligibility.
If you’re unsure which option is best for you, our team will be happy to guide you during your consultation.
Get in Touch
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