Regenerate your skin from within with Polynucleotides
Fade dark circles, smooth fine lines, and boost natural skin repair from the inside out all with clinically proven Polynucleotide therapy.
- Fade dark circles
- Smooth fine lines
- Cellular rejuvenation
Regenerate your skin from within with Polynucleotides
Fade dark circles, smooth fine lines, and boost natural skin repair from the inside out all with clinically proven Polynucleotide therapy.
- Fade dark circles
- Smooth fine lines
- Cellular rejuvenation
What are Polynucleotides?
A next-generation regenerative treatment that activates your skin’s own healing power, working with your biology, not against it.
Polynucleotides are purified DNA fragments that awaken your skin’s natural repair processes to restore hydration, firmness, and elasticity from deep within.
Rather than filling or freezing the skin, they work at a cellular level to improve hydration, elasticity, texture, and overall skin quality over time.
This makes polynucleotides ideal for patients looking for natural-looking rejuvenation, improved skin resilience, and long-term skin health.
Often integrated into advanced treatment plans, polynucleotides can complement procedures such as CO₂ laser or microneedling to optimise healing and long-term skin regeneration.
What Can Polynucleotides Improve?
Polynucleotide treatments can improve a range of skin concerns at a deeper level, restoring your skin's quality and health
Dull, dehydrated skin
Deeply rehydrates and revitalizes your complexion for a healthier, more luminous glow.
Fine lines & wrinkles
Smooths fine lines and refines texture, restoring youthful softness and suppleness.
Loss of elasticity
Boosts skin firmness and resilience by supporting renewed collagen production.
Under-eye area
Brightens and thickens delicate under-eye skin to reduce tiredness and dark circles.
Crepey skin
Improves skin density and tone, giving thin areas a firmer, silkier feel.
Post-procedure skin repair
Accelerates healing and enhances recovery after aesthetic treatments.
Is Polynucleotides Right For You?
Polynucleotides are ideal for patients who want skin improvement that looks natural, refined, and gradual.
✔ This Treatment Is Ideal If You:
✖ Polynucleotides May Not Be Right If You:
Where Are Polynucleotides Used?
Polynucleotides are perfect for rejuvenating delicate, high-movement areas where precision, safety, and subtle results matter most.
What to Expect After Treatment
Polynucleotides work gradually, enhancing your skin’s natural renewal with visible improvements week by week.
Most treatment plans involve 2–3 sessions spaced 2–4 weeks apart, with maintenance recommended every 6–12 months depending on your goals.
Day 0-3
Skin may feel slightly flushed or tight
minimal downtime
early hydration.
Week 1-2
Skin texture begins to smooth
Improved hydration and elasticity
Early quality changes becomes noticeable
Long-Term Regeneration
Ongoing collagen support
Progressive improvement in skin quality
Results continue developing over several weeks
Treatment Options & Pricing
Under-Eye Area
- Targets the delicate under-eye area
- brighten and rejuvenate tired skin
- Improves crepey texture & hydration
Upper or Lower Face Focus
- Improves elasticity & skin quality
- Ideal for targeted regeneration
Full Face
- Whole-face regeneration
- Improves texture, tone & hydration
- Best long-term skin quality results
Transparent pricing. Trusted clinical standards.
Everything you need to feel confident in your treatment.
What to expect with polynucleotide treatment
Polynucleotides are regenerative skin treatments designed to support cellular repair, improve elasticity, and enhance overall skin quality through targeted microinjections.
This advanced bio-stimulatory approach works beneath the surface to encourage natural tissue repair and collagen support over time.
We prioritise subtle, progressive improvement and medically delivered precision.
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Polynucleotides. Your Questions, Answered.
What are polynucleotides and how do they work?
Polynucleotides are purified DNA fragments that stimulate cellular repair and collagen production.
Rather than adding volume like filler, they:
• Improve skin quality
• Support regeneration
• Increase hydration
• Strengthen the dermal structure
They work by activating your skin’s natural repair response.
What brand of Polynucleotides do you use?
We use Plinest, a high-quality, medical-grade polynucleotide treatment known for its purity, safety, and clinically proven results. Plinest is widely used in advanced aesthetic medicine to support skin regeneration, improve texture, and enhance overall skin quality.
Is this the same as Dermal Filler?
No.
Dermal fillers add volume immediately.
Polynucleotides improve skin quality gradually by stimulating regeneration and collagen remodelling.
The result is more natural and progressive.
What areas can be treated?
Common areas include:
• Under-eyes
• Face
• Neck
• Décolletage
They are particularly popular for delicate under-eye rejuvenation.
Is it safe for the under eye?
Yes when performed correctly.
Polynucleotides are often chosen specifically for under-eye treatment because they improve skin quality without adding heavy volume.
A consultation ensures correct placement and suitability.
How many sessions do I need?
Most clients require 2–3 sessions spaced 2–4 weeks apart.
Maintenance may be recommended every 6–9 months depending on skin goals.
When will I see results?
Some improvement in hydration and glow can appear within weeks.
Collagen stimulation continues progressively over 8–12 weeks.
Results improve gradually rather than instantly.
What is the downtime?
You may experience:
• Mild swelling
• Small injection bumps
• Light bruising
These typically settle within 24–72 hours.
Most clients return to normal activities quickly.
Can I combine with other treatments?
Yes.
Polynucleotides are often combined with:
• Anti-wrinkle treatments
• Skin boosters
• CO₂ resurfacing
• Microneedling
Your consultation determines safe sequencing.
Who may not be suitable?
This treatment may not be suitable if:
• Pregnant or breastfeeding
• Active infection in treatment area
• Certain autoimmune conditions
A consultation ensures safety.
What payment options do you offer?
We offer flexible payment options to make your treatment as convenient as possible. You can choose to pay per single session or pay in full for a course of treatments for better overall value. We accept card, cash, and bank transfer in clinic.
For added flexibility, we also offer 0% finance through Klarna, allowing you to spread the cost into manageable instalments with a range of payment options available, subject to eligibility.
If you’re unsure which option is best for you, our team will be happy to guide you during your consultation.
Location & Contact
Find Us / Visit the Clinic
Address: Laser Skin Clinics & Aesthetics Wolverhampton, 4 Perton Farm Barns, Jenny Walkers Ln, Wolverhampton, WV6 7HB.
Opening Hours:
- Tue, Wed, Fri: 10:00 - 18:00
- Sat: 10:00 - 16:00
- (Closed Mon, Thu, Sun)